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inflammation

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Risk Factors
July 12, 2023

Long COVID ‘Brain Fog’ Confounds Doctors, but New Research Offers Hope

James C. Jackson, PsyD, a licensed psychologist specializing in neuropsychology and rehabilitation, at Vanderbilt University School of Medicine and author of a new book, Clearing the Fog: From Surviving to Thriving With Lo...
Treatments
July 2, 2023

Lumateperone Normalizes Pathological Levels of Acute Inflammation and Stimulates Important Pathways Involved in Mood Regulation

Highlights from Posters Presented at the Society of Biological Psychiatry Meeting, April 27-29, 2023 in San Diego -- Sophie Dutheil of Intra-Cellular Therapies, Inc. reported that “In male and female C57BL/6 mice subjected...
Biology
May 5, 2020

Translocator Protein Levels in Brain Predict Response to Anti-Inflammatory Celecoxib in Major Depressive Disorder

Photo by Robina Weermeijer on Unsplash -- Gliosis describes changes in glia that result from damage to the central nervous system. Researchers can use PET scans (positron emission tomography) to measure the extent of glios...
Biology
February 14, 2019

Inflammation Associated With Duration of Untreated Unipolar Depression

Researcher Sophia Attwells and colleagues reported at a 2018 scientific meeting that the longer the time that a patient went without treatment for depression, the more inflammation they exhibited on positron emission tomog...
Biology
February 14, 2018

Depression and Suicidal Thoughts Linked to Brain Inflammation

A 2017 article by Sophie E. Holmes and colleagues in the journal Biological Psychiatry reports that people with major unipolar depression, especially those with suicidal thoughts, have higher levels of the inflammatory mar...
Biology
April 12, 2017

Immune Response to Repeated Stress Alters Behavior in Mice

In research presented at the 2016 meeting of the Society of Biological Psychiatry, Jonathan P. Godbout described how an immune reaction to repeated stressors may lead to anxious behaviors in mice. -- Mice were repeatedly d...
Biology
April 5, 2017

Mysteries Remain in the Relationship Between Inflammation and Depression

At the 2017 meeting of the American College of Psychiatrists, researchers Charles L. Raison and Vladimir Maletic gave a plenary lecture on the role of inflammation in depression. Meta-analyses have confirmed that inflammat...
Biology
April 4, 2017

How Stress Triggers Inflammation and Depression

Depression and bipolar disorder are associated with increases in markers of inflammation that can be found in the brain and blood. It is increasingly clear that the mechanisms that cause depression are not just in the brai...
Biology
March 14, 2017

Measuring Inflammation in Neuropsychiatric Disorders May Shed Light on Treatment

Meta-analyses have found links between elevated levels of inflammatory markers and many neuropsychiatric disorders, including depression, bipolar disorder, schizophrenia, post-traumatic stress disorder (PTSD) and traumatic...
Biology
December 14, 2016

Brain Inflammation Found in Autopsy Studies of Teen and Adult Suicides

Suicide and depression have both been linked to elevated levels of inflammatory cytokines in the blood and cerebrospinal fluid. A recent study finds that these inflammatory markers are also elevated in the brains of teens ...
Biology
December 6, 2016

Certain Types of Inflammation and BMI Predict Depression

At the 2016 meeting of the Society of Biological Psychiatry, researcher Femke Lamers and colleagues presented findings from the Netherlands Study of Depression and Anxiety. The inflammatory markers interleukin-6 and CRP we...
Biology
June 22, 2016

Some Evidence of Brain Inflammation in Depression

Many studies have found links between levels of inflammatory molecules in the blood and depression or depressive symptoms. There has been less research about inflammation in the brain and its possible role in depressive il...
Biology
January 20, 2016

Brain Inflammation in People at High Risk for Schizophrenia

Microglial activity in the brains of people who are healthy, people at high risk for schizophrenia, and people who have been diagnosed with schizophrenia. -- A 2016 study by Peter S. Bloomfield and colleagues in the Americ...
Biology
January 6, 2016

Reduced Cognitive Function and Other Abnormalities in Pediatric Bipolar Disorder

At the 2015 meeting of the International Society for Bipolar Disorders, Ben Goldstein described a study of cognitive dysfunction in pediatric bipolar disorder. Children with bipolar disorder were three years behind in exec...
Biology
September 16, 2015

Blood and Now Brain Inflammation Linked to Depression

There is growing evidence of a link between inflammation of depression. At the 2015 meeting of the Society of Biological Psychiatry, researcher Jeff Meyer summarized past studies on inflammatory markers. These are measurem...
Biology
July 12, 2010

Inflammation in the Affective Disorders

Bipolar children exhibit more inflammation than healthy children, according to a paper presented by Pandey, Dwivedi, and Pavuluri from the University of Illinois at the American College of Neuropsychopharmacology in Decemb...