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white matter

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Biology
February 17, 2024

Bipolar I patient show dramatic reductions in white matter integrity

Thiel et al in Neuropsychopharmacology (2024) reported that “Compared with HC [healthy controls], BD-I patients exhibited lower FA [fractional anisotropy] in widespread clusters (ptfce-FWE?< 0.001), including almost all ma...
Biology
July 18, 2023

Changes in brain structure in remitted bipolar patients

Macoveanu et al reported in the Journal of Affective Disorders (2023) that compared to controls that remitted bipolar patients had “a decline in total white matter volume over time and they had a larger amygdala volume, bo...
Risk Factors
July 12, 2023

Long COVID ‘Brain Fog’ Confounds Doctors, but New Research Offers Hope

James C. Jackson, PsyD, a licensed psychologist specializing in neuropsychology and rehabilitation, at Vanderbilt University School of Medicine and author of a new book, Clearing the Fog: From Surviving to Thriving With Lo...
Biology
July 7, 2023

Both Obesity and Bipolar Disorders in 2249 Individuals Show White Matter Microstructure Abnormalities

Lorielle Dietze of Dalhousie University “obtained body mass index (BMI) and diffusion tensor imaging derived fractional anisotropy (FA) values from 930 individuals with bipolar disorders (BD), and 1319 control individuals ...
Biology
July 6, 2023

Cognitive Function and White Matter Integrity in Individuals With Bipolar Disorder

Highlights from Posters Presented at the Society of Biological Psychiatry Meeting, April 27-29, 2023 in San Diego -- Jennifer McDowell reported that they found “significantly reduced FA (fractional anisotropy) values in 85...
Biology
July 7, 2020

White Matter Disturbances in Bipolar Disorder

At the 2020 meeting of the International Society for Bipolar Disorders, researcher Clare Beasley described the cellular and molecular underpinnings of the white matter abnormalities typically seen in children and adults wi...
Biology
July 23, 2019

Lithium Reverses Some White Matter Abnormalities in Youth with Bipolar Disorder

Multiple groups of researchers have reported the presence of white matter tract abnormalities in patients with bipolar disorder. Some of these abnormalities correlate with the degree of cognitive dysfunction in these patie...
Biology
January 16, 2019

White Matter Abnormalities in Obesity

Researcher Ramiro Reckziegel and colleagues reported at a recent scientific meeting that white matter is abnormal in obese adults with bipolar disorder. In a 2018 article in the journal Schizophrenia Bulletin, Reckziegel r...
Biology
January 14, 2019

White Matter Abnormalities Linked to Irritability in Both Bipolar Disorder and DMDD

At a 2018 scientific meeting, researcher Julia Linke of the National Institute of Mental Health reported that there were white matter tract abnormalities in young people who had irritability associated with either bipolar ...
Biology
September 29, 2017

Brain Scans Differentiate Suicidal from Non-Suicidal Patients with Bipolar Disorder

People with bipolar disorder are at high risk for suicidal behavior beginning in adolescence and young adulthood. A 2017 study by Jennifer A. Y. Johnston and colleagues in the American Journal of Psychiatry uses several br...
Biology
July 27, 2017

Marker of Heart Failure May Predict Brain Deterioration

A protein released into the blood in response to heart failure may be able to predict brain deterioration before clinical symptoms appear. The protein, N-terminal pro-B-type natriuretic peptide (NT-proBNP), is released whe...
Biology
May 11, 2016

Poverty Early in Life Decreases White Matter Integrity in the Brain

One-fifth of children in America grow up in poor families. Poverty can affect development, health, and achievement, and new evidence shows it even affects brain structure. -- New unpublished research suggests that early po...
Childhood
January 18, 2016

Schizophrenia: The Importance of Catching It Early

By the time psychosis appears in someone with schizophrenia, biological changes associated with the illness may have already been present for years. A 2015 article by R.S. Kahn and I.E. Sommer in the journal Molecular Psyc...
Biology
January 6, 2016

Reduced Cognitive Function and Other Abnormalities in Pediatric Bipolar Disorder

At the 2015 meeting of the International Society for Bipolar Disorders, Ben Goldstein described a study of cognitive dysfunction in pediatric bipolar disorder. Children with bipolar disorder were three years behind in exec...
Biology
July 31, 2015

Neuropsychological Deficits After Concussion Are Correlated with White Matter Abnormalities

DTI brain scan can show damage to white matter following a concussion. -- Many people suffer problems with mental functioning after an apparent concussion (otherwise known as mild traumatic brain injury, or mTBI) that does...
Biology
June 13, 2013

Meditation Improves Mood and White Matter Integrity

New research shows that regular meditation in the form of mindfulness training improves both mood and measures of white matter (axon tract) integrity and plasticity in the anterior cingulate cortex (a key node in the brain...